Poliovirus Receptor Protein (PVR) (C-Term, Extracellular Domain)

N° du produit ABIN1684657

Cette protéine Recombinant Poliovirus Receptor est produite dans HEK-293T Cells.

Aperçu rapide pour Poliovirus Receptor Protein (PVR) (C-Term, Extracellular Domain) (ABIN1684657)

Antigène: Poliovirus Receptor (PVR)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: HEK-293T Cells

Pureté: > 95 %, as determined by SDS-PAGE and HPLC

Détail du produit

Attributs du protein: C-Term, Extracellular Domain

Specificité: Optimized DNA sequence encoding extracellular domain of Mouse PVR CD155 including a C-terminal 6His tag was expressed in HEK293 cells.

Attributs du produit: Recombinant mouse PVR (CD155) is a monomer protein consisting of 329 amino acid residue subunits, due to glycosylation migrates as an approximately 55-60 kDa protein on SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Information d'application

Commentaires:

The biological activity of Mouse PVR was measured by the binding ability of immobilized recombinant Mouse CD155 (1 µg/mL100 µL/well ) to mouse CD226 (linear range of 1 - 100 g/mL) in a functional ELISA assay.

Restrictions: For Research Use only

Stockage

Buffer: PBS solution, pH7.2

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

Date de péremption: 12-24 months

Détail du antigène

Antigène: Poliovirus Receptor (PVR)

Autre désignation: CD155

Sujet: M-CSF is produced by monocytes, granulocytes, endothelial cells, and fibroblasts. After cell activation, B-cells and T-cells and also a number of tumor cell lines are capable also of synthesizing this factor. M-CSF has been found to be synthesized by uterine epithelial cells in vivo. The M-CSF receptor is identical with the proto-oncogene fms. It has been renamed CD115. The receptor is a transmembrane protein with an extracellular ligand-binding domain of 512 amino acids, an intramembrane domain of5 amino acids, and a cytoplasmic domain of 435 amino acids encoding a tyrosine kinase. Human M-CSF is active in mouse and rat cells. The murine factor is active in rat cells but inactive in human cells. M-CSF is a specific factor in that the proliferation inducing activity is more or less restricted to the macrophage lineage. M-CSF is a potent stimulator of functional activities of monocytes.

UniProt: Q8K094

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome